Plant-Derived Arginine

Origin

This basic amino acid is derived from plant-based sources such as corn and cassava.

Skincare Benefits

Within the skin’s stratum corneum, Natural Moisturizing Factors (NMFs) play a vital role in retaining hydration.

Amino acids make up approximately 40% of the NMF, and about 10% of these amino acids consist of arginine.

Arginine is found not only in the stratum corneum, but also throughout the epidermis, dermis, and subcutaneous tissue.

It is notably abundant in collagen fibers, which make up roughly 70% of the dermis, supporting the skin’s firmness and elasticity.

Arginine is an essential amino acid for children, but becomes a non-essential amino acid for adults, as the body can synthesize it naturally.

It is known to stimulate growth hormone secretion, enhance blood circulation, and support immune function, which is why it is widely used in dietary supplements and energy drinks.

In cosmetics, arginine functions as a humectant, attracting and retaining moisture in the skin.

Being a water-soluble, low-molecular-weight zwitterionic compound, it does not easily penetrate healthy skin, allowing it to act as a gentle and long-lasting moisturizer.

However, in skin with a weakened barrier—such as in cases of dryness or atopic dermatitis—arginine demonstrates increased permeability, helping to restore and balance the skin’s condition.

Arginine is listed in the Japanese Standards for Quasi-drug Ingredients (2021), the Japanese Pharmacopoeia, and the existing food additive list, with over 50 years of safe use.

It is considered non-irritating and non-allergenic, making it highly suitable for sensitive skin formulations.